Brain-specific heterozygous loss-of-function of ATP2A2, endoplasmic reticulum Ca2+ pump responsible for Darier's disease, causes behavioral abnormalities and a hyper-dopaminergic state.

Human molecular genetics

Kazuo Nakajima, Mizuho Ishiwata, Adam Z Weitemier, Hirotaka Shoji, Hiromu Monai, Hiroyuki Miyamoto, Kazuhiro Yamakawa, Tsuyoshi Miyakawa, Thomas J McHugh, Tadafumi Kato