An inhaled ACE2 decoy confers protection against SARS-CoV-2 infection in preclinical models.

Science Translational Medicine. 15:eadi2623

Urano E, Itoh Y, Suzuki T, Sasaki T, Kishikawa J, Akamatsu K, Higuchi Y, Sakai Y, Okamura T, Mitoma S, Sugihara F, Takada A, Kimura M, Nakao S, Hirose M, Sasaki T, Koketsu R, Tsuji S, Yanagida S, Shioda T, Hara E, Matoba S, Matsuura Y, Kanda Y, Arase H, Okada M, Takagi J, Kato T,Hoshino A, Yasutomi Y, Saito A, Okamoto T.